Associate Director, Clinical AI Translation & Solutions
AstraZeneca1 day ago
Base Salary
$145k - $217k/yr
Responsibilities
- Own clinical AI workflow portfolios from discovery through deployment, adoption, and measurable benefit realization.
- Observe clinical workflows and translate stakeholder pain points into product requirements, data contracts, acceptance criteria, and evaluation plans.
- Build and iterate Python prototypes, contribute production code, review pull requests, inspect logs, reproduce failures, and resolve issues with engineers.
- Design agentic workflows combining language models, deterministic services, enterprise tools, and human review with provenance, uncertainty handling, and fail-safe behavior.
- Define technical, clinical, workflow, adoption, cycle-time, and operational outcome measures.
- Lead human-in-the-loop testing with clinical experts and convert feedback into prioritized product changes.
- Partner with data-product owners and platform teams to provide reliable, privacy-preserving access to clinical systems and data.
- Embed GCP, GxP, validation, auditability, privacy, security, and lifecycle requirements into AI solutions.
- Promote reuse and make build, buy, partner, and adapt decisions for platforms, data products, agent components, and evaluation assets.
- Communicate product decisions, evidence, risks, dependencies, and trade-offs to technical teams, clinical leaders, and executives.
- Mentor scientists and engineers and raise standards for product thinking, technical execution, and clinical partnership.
Requirements
- PhD in computer science, machine learning, statistics, biomedical informatics, computational biology, or a related quantitative discipline; or an MD, master's degree, or equivalent experience supported by a strong computational track record.
- 4 to 7 years of post-PhD or equivalent experience delivering applied AI/ML or data products, including experience in healthcare, life sciences, clinical research, or another high-consequence domain.
- Current hands-on coding ability in Python and SQL, with experience using version control, tests, APIs, data pipelines, and modern cloud or containerized development environments.
- Experience building or deploying LLM-based or agentic systems with retrieval, tool use, structured outputs, workflow orchestration, and human review.
- Ability to translate ambiguous stakeholder needs into bounded products, working prototypes, measurable acceptance criteria, and delivery plans.
- Experience leading workflow-discovery and design sessions with clinical professionals and communicating clinical, operational, and regulatory constraints clearly.
- Experience evaluating AI systems using technical metrics and expert judgment when ground truth is noisy, incomplete, or context dependent.
- Strong understanding of trustworthy AI practices, including provenance, access control, and uncertainty handling.
- Excellent written and verbal communication across engineering, scientific, clinical, quality, and executive audiences.
- Evidence of leading cross-functional delivery through influence, including prioritization, conflict resolution, and shipping decisions under ambiguity.
- Experience with clinical trial conduct, site monitoring, risk-based monitoring, medical monitoring, clinical data review, or trial technology is desirable.
- Working knowledge of GCP and GxP computerized-system validation is desirable.
- Experience with clinical systems and data such as CTMS, EDC, eTMF, safety systems, EHR, monitoring reports, or clinical data platforms is desirable.
- Experience designing reusable product capabilities across therapeutic areas, studies, or business units is desirable.
- Familiarity with observability, LLMOps/MLOps, and production monitoring for deployed AI systems is desirable.
- Publications, patents, open-source contributions, or a record of shipping technically differentiated AI products are desirable.
Benefits
- Annual base pay ranges from $144,648.8 to $216,973.2 USD.
- May be eligible for short-term incentive bonuses and equity-based awards for salaried roles.
- Benefits may include qualified retirement programs, paid time off including vacation, holidays, and leave, plus health, dental, and vision coverage.
- Hybrid work arrangement is indicated by the #LI-Hybrid designation.
- AstraZeneca provides disability accommodations and promotes an inclusive, discrimination-free workplace.
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About AstraZeneca
AstraZeneca is a global biopharmaceutical company that discovers, develops, manufactures, and commercializes prescription medicines for patients and healthcare systems. Its portfolio spans oncology, cardiovascular, renal and metabolism, respiratory and immunology, and rare diseases (expanded by the 2021 acquisition of Alexion). Founded in 1999 and headquartered in Cambridge, UK, it is a public company listed on the London Stock Exchange and Nasdaq, generating revenue primarily from drug sales and partnerships.