Senior Software Engineer, Bioinformatics
Guardant HealthBase Salary
$150k - $207k/yr
Responsibilities
- Design, develop, test, deploy, and maintain software applications and services supporting bioinformatics and clinical workflows.
- Build scalable Python backend services and APIs using Django, FastAPI, or similar web frameworks.
- Develop responsive user interfaces using React and modern frontend technologies.
- Design and optimize PostgreSQL schemas, queries, performance, and data integrity.
- Architect, deploy, and operate applications in AWS environments.
- Apply automated testing, code review, CI/CD, observability, security, and infrastructure automation practices.
- Collaborate with bioinformatics scientists, computational biologists, product managers, quality teams, and distributed cross-functional stakeholders.
- Develop software for scientific datasets, analytical workflows, and computational pipelines.
- Use and evaluate AI-assisted software development tools for coding, testing, debugging, code review, documentation, and developer workflows.
- Produce technical documentation, architecture specifications, design documents, and operational procedures.
- Contribute to architectural decisions, development standards, and engineering best practices.
- Troubleshoot production issues, perform root-cause analysis, and implement long-term corrective solutions.
- Mentor engineers and contribute to the technical growth of the engineering organization.
Requirements
- Bachelor’s degree in Computer Science, Software Engineering, Bioinformatics, Computational Biology, or a related technical discipline, or equivalent practical experience.
- At least 5 years of professional software development experience with significant hands-on Python development.
- Strong experience with Python web frameworks such as Django and FastAPI.
- Experience building modern web applications with React, JavaScript or TypeScript, HTML, and CSS.
- Strong relational database experience, particularly PostgreSQL, including schema design, queries, optimization, and data integrity.
- Hands-on experience developing, deploying, and supporting applications in AWS.
- Understanding of RESTful APIs, distributed systems, service-oriented architectures, and modern application design.
- Experience with automated testing, source control, code review, CI/CD, and modern DevOps practices.
- Experience using AI-enabled software engineering tools for coding, testing, debugging, code review, or documentation.
- Ability to solve complex technical problems with limited supervision and manage multiple priorities.
- Strong written and verbal communication and effective collaboration with geographically distributed, cross-functional teams.
- Preferred: experience in life sciences, biotechnology, genomics, healthcare, clinical diagnostics, bioinformatics, genomic data, computational pipelines, or scientific computing.
- Preferred: experience with regulated software, FDA requirements, quality regulations, requirements traceability, design controls, verification and validation, change control, and documentation.
- Preferred: experience with Docker, Kubernetes, AWS ECS/EKS, Lambda, RDS, S3, CloudWatch, IAM, Terraform, or AWS CDK.
- Preferred: experience designing systems for large scientific or clinical datasets and familiarity with healthcare data privacy, security, and compliance.
Benefits
- Hybrid work model with in-person collaboration on Mondays, Tuesdays, and Thursdays and work-from-home days for eligible U.S. employees living within 50 miles of a Guardant facility.
- Reasonable accommodations are available for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs.
- Equal opportunity employment and confidential handling of applicant information.
- A background screening, including criminal history, is required.
- The role is primarily desk/office-based but may involve laboratory exposure to noise, fumes, and biohazard material.
Tech Stack
Categories
About Guardant Health
Guardant Health is a leading precision medicine company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, we're transforming patient care by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant® tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. Important Note for Job Applicants: Guardant Health is aware of recruiting scams where unauthorized individuals use the company's name in fraudulent emails, job postings, and social media messages. Please note that Guardant Health will never ask for money or credit card information during the job application process, nor does the company communicate with candidates via online chatrooms or personal email accounts such as Gmail or Hotmail.