Lila Sciences

Principal Machine Learning Engineer, Applied AI

Lila Sciences
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10 hours ago
Cambridge, MA, USA or San Francisco, CA, USAStaff+
H1B sponsor

Base Salary

$252k - $336k/yr

Responsibilities

  • Lead model post-training efforts using SFT and reinforcement learning methods such as DPO, PPO, and GRPO.
  • Build and operate evaluation loops measuring model quality, reliability, and customer fit.
  • Translate customer learnings, data signals, and evaluation results into model improvement cycles.
  • Partner with AI researchers to translate model advances into reliable capabilities.
  • Work with software teams to integrate model behavior into end-to-end product workflows.
  • Debug complex model failures using traces, evaluations, customer context, scientific feedback, data, and logs.
  • Mentor engineers and share reusable patterns for model adaptation, evaluation, and deployment.
  • Lead technical work across research and engineering teams.

Requirements

  • At least 2–3 years of hands-on post-training experience and evaluation system design.
  • Strong software engineering skills in Python and modern ML frameworks such as PyTorch.
  • Experience debugging ambiguous, high-stakes model behavior using data, traces, logs, and qualitative feedback.
  • Deep familiarity with large language models, multimodal models, or agentic AI systems.
  • Clear communication skills for translating customer needs into technical approaches and explaining complex model behavior.
  • Preferred experience adapting models for customer-facing or production workflows in scientific, technical, or data-intensive domains.
  • Preferred experience with RL post-training such as RLHF, GRPO, or tool-augmented RL.
  • Preferred experience building evaluation harnesses, model monitoring, or quality dashboards.
  • Experience training mixture-of-experts architectures is a bonus.
  • A track record of mentoring engineers and serving as a go-to technical expert is preferred.

Benefits

  • Full-time U.S. employees receive medical, dental, and vision coverage.
  • Benefits include employer-paid life and disability insurance, flexible time off, generous company-wide holidays, and paid parental leave.
  • The company provides educational assistance, commuter benefits including bike share memberships for office-based employees, and a subsidized lunch program.
  • International employees receive a comprehensive benefits program tailored to their region.
  • The compensation package includes bonus potential and early-stage equity.

Tech Stack

Categories

Lila Sciences

About Lila Sciences

501-1,000 employees

Lila Sciences builds an AI-driven research platform and autonomous lab systems for life science, chemistry, and materials R&D teams. Its products combine large AI models with robotic instruments to plan, run, and analyze experiments, integrating into customer-specific scientific workflows. The privately held company serves pharma, materials, and energy organizations and is venture-backed, including a Series A financing in 2025.

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