Genesis Molecular AI

Fullstack Software Engineer (Senior / Staff)

Genesis Molecular AI
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8 months ago
San Mateo, CA, USA or New York, NY, USASenior / Staff+

Responsibilities

  • Own and evolve the full-stack platform for computational chemists, including data exploration, experiment management, visualization, and AI-native workflows.
  • Build tools for visualizing molecules and proteins, analyzing machine learning models, and managing complex chemical workflows.
  • Partner with machine learning engineers and computational chemists to develop and productionize computational methods for molecular property prediction.
  • Scale data infrastructure to support billions of datapoints and thousands of parallel deep learning and molecular dynamics jobs.
  • Ship production code and drive projects end-to-end with minimal supervision.

Requirements

  • Experience shipping production software and driving projects end-to-end with minimal hand-holding.
  • Ability to work across frontend interfaces, backend services, data pipelines, and infrastructure.
  • Strong architectural thinking, attention to detail, investigative curiosity, and first-principles reasoning.
  • Interest in the intersection of software engineering, drug discovery, and machine learning.

Benefits

  • Opportunity to build high-impact tools directly used to accelerate the discovery of new medicines.
  • Collaboration with technical coworkers in AI, software, and chemistry, including regular machine learning and chemistry paper discussions.
  • Competitive salary and equity.
  • Medical, dental, and vision insurance.
  • 401(k) program.
  • Position is based at Genesis Molecular AI, headquartered in San Mateo, California, with a laboratory in San Diego; the posting does not state a remote or hybrid arrangement.

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Genesis Molecular AI

About Genesis Molecular AI

51-200 employees

Genesis Molecular AI develops GEMS, a generative and predictive molecular AI platform that designs and optimizes small‑molecule drug candidates, including the Pearl diffusion model for structure prediction. The company advances an internal discovery pipeline and partners with pharma on AI‑enabled discovery; recent collaborations include Gilead (2024) and Incyte (2025). It is privately held, headquartered in Burlingame, California, with a fully integrated laboratory in San Diego.

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