St. Jude Children's Research Hospital

Senior Artificial Intelligence Engineer

St. Jude Children's Research Hospital
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1 month ago
Memphis, TN, USASenior

Base Salary

$86k - $155k/yr

Responsibilities

  • Assess institutional needs and implement AI-enabled services on high-performance AI computing platforms.
  • Design, develop, deploy, fine-tune, evaluate, and benchmark AI/ML models and solutions, including LLMs, agentic systems, and multimodal foundation models.
  • Build shared AI architecture, secure environments, safety guardrails, sandboxing, and reproducible evaluation frameworks.
  • Optimize distributed and multi-GPU training and inference, HPC scheduling, GPU utilization, cost, latency, and resource efficiency.
  • Safeguard sensitive research data through access controls, privacy practices, secrets management, audit logging, and institutional security policies.
  • Own AI systems beyond the prototype stage, including observability, versioning, rollback, cost control, and incident response.
  • Develop standards, operating procedures, architecture roadmaps, reference architectures, demonstrations, workshops, and training materials.
  • Collaborate with scientists, business stakeholders, analysts, information systems professionals, teams, and vendors.
  • Evaluate commercial and open-source AI/ML, data mining, and analytics approaches for non-trivial business and research problems.

Requirements

  • Master's degree in computer science, computer engineering, data science, information technology, or a related field.
  • At least 4 years of experience designing and developing large-scale AI/ML systems or building AI/ML product features.
  • Strong experience with deep learning, supervised and unsupervised machine learning, and industry AI use cases.
  • Experience with TensorFlow, Keras, PyTorch, time series analysis, anomaly detection, forecasting, predictive modeling, graph-based neural networks, Bayesian statistics, and text analytics.
  • Preferred hands-on experience training, fine-tuning, or adapting LLMs or multimodal foundation models, including PEFT/LoRA, instruction tuning, and preference optimization.
  • Preferred experience troubleshooting distributed or multi-GPU training and inference, CUDA and NCCL issues, HPC scheduling with Slurm, and GPU utilization across nodes.
  • Preferred experience designing agentic-system safety guardrails, tool-access scoping, prompt-injection defenses, secrets management, audit logging, and failure containment.
  • Preferred experience optimizing inference through KV-cache management, quantization, batching, speculative decoding, and high-throughput serving.
  • Preferred experience building scalable AI/ML pipelines on HPC or cloud environments and rigorous benchmarking frameworks.
  • Preferred contributions to open-source AI/ML infrastructure or a public technical track record through GitHub, Hugging Face, or papers.
  • PhD in data science, computer science, computer engineering, information technology, or a related field is preferred.
  • Biomedical research, imaging, regulated health data, technical leadership, mentoring, standards-setting, and cross-team collaboration experience are preferred.

Benefits

  • Onsite work arrangement in Memphis, Tennessee.
  • Estimated salary range of $86,320-$154,960 per year.
  • Benefits are offered, with details available through St. Jude's exceptional benefits program.
  • Human-centered hiring process with human review and engagement in recruiting decisions.

Tech Stack

KerasPyTorchTensorFlow

Categories

St. Jude Children's Research Hospital

About St. Jude Children's Research Hospital

10,000+ employees

St. Jude Children’s Research Hospital is a nonprofit pediatric research hospital that treats children with cancer and other life‑threatening diseases and advances therapies through in-house labs, clinical trials, and data resources like St. Jude Cloud. Founded in 1962 and headquartered in Memphis, Tennessee, it is funded primarily by public donations raised by ALSAC and by research grants. The hospital provides care regardless of a family’s ability to pay and collaborates globally.

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