Hologic, Inc.

Software AI Engineer 4

Hologic, Inc.
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3 days ago
Marlborough, MA, USASenior

Base Salary

$133k - $190k/yr

Responsibilities

  • Design, train, tune, and validate multi-class CNNs and multi-task models for cell classification, cytomorphologic features, and diagnostic categories.
  • Develop nucleus and cytoplasm segmentation networks to measure nuclear-to-cytoplasmic ratios and nuclear areas, including in overlapping cell clusters.
  • Own patient-grouped data splits, color processing, class balancing, imaging metadata, experiment tracking, reproducible training, and evaluation reporting.
  • Collaborate with cytopathologists on labeling protocols, inter-observer agreement, and adjudication processes.
  • Prepare design documentation, verification and validation protocols, and regulatory-submission technical content under design controls.
  • Ensure model performance and interpretability through metrics, Grad-CAM checks, and feature outputs aligned with pathologist expectations.
  • Mentor engineers and establish coding, reproducibility, and MLOps standards.

Requirements

  • MS or PhD in computer science, biomedical engineering, electrical engineering, or a related field, or a BS with equivalent experience.
  • At least 7 years of software development experience, including at least 4 years building and deploying deep learning models for computer vision.
  • Expert Python and PyTorch or TensorFlow skills, including CNN fine-tuning, transfer learning, and segmentation.
  • Experience with imbalanced, multi-class, and multi-task problems and metrics including per-class sensitivity, F1, kappa, and AUROC.
  • Experience with medical or microscopy imaging, color handling, stain variation, and high-resolution tiling.
  • Strong practices for data splitting, leakage prevention, experiment tracking, and reproducible training.
  • Clear written communication for technical reports and design documentation.
  • Preferred experience includes digital pathology or cytology AI, FDA 510(k), De Novo or PMA submissions, EU IVDR, IEC 62304, ISO 13485, ISO 14971, 21 CFR Part 820, and FDA PCCP guidance.
  • Preferred experience includes ICC color management, stain deconvolution, scanner color calibration, cell instance segmentation, annotation tools, edge or embedded inference optimization, and technical leadership of a small team.

Benefits

  • Comprehensive onboarding training and continued development and training throughout the career.
  • Annualized base salary range of $133,000 to $190,000 plus bonus eligibility.
  • Equal opportunity employment.

Tech Stack

PythonPyTorchTensorFlow

Categories

Hologic, Inc.

About Hologic, Inc.

5,001-10,000 employees

Hologic builds breast and skeletal imaging systems, molecular diagnostic platforms and assays, and GYN surgical devices used by hospitals, imaging centers, and clinical labs. Its business model combines capital equipment sales with recurring revenue from consumables, assays, and service contracts. Founded in 1985 and headquartered in Marlborough, Massachusetts, Hologic is listed on Nasdaq (HOLX) and is associated with 3D mammography and the Panther molecular testing platform.

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