Lila Sciences

Machine Learning Scientist I / II, Protein Design

Lila Sciences
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7 hours ago
San Francisco, CA, USAEntry Level / Mid Level
H1B sponsor

Base Salary

$176k - $304k/yr

Responsibilities

  • Design molecules for active biologics programs in partnership with domain scientists.
  • Develop reasoning capabilities and orchestrate computational design workflows for drug discovery.
  • Design and maintain benchmarks and evaluation infrastructure for biologics design workflows.
  • Own reproducibility, throughput, and inference-cost operations for computational design systems.
  • Translate domain-scientist judgment into machine learning objectives and evaluation criteria.
  • Connect specialist protein design models to the broader autonomous science platform.

Requirements

  • MS or PhD in computer science, machine learning, computational biology, biophysics, bioengineering, or a similar quantitative field.
  • Strong software engineering and system design fundamentals.
  • Expertise in evaluation and dataset design, including benchmark leakage and downstream validation quality.
  • Strong cross-functional communication skills.
  • Domain expertise in protein sequence, structure, and function.
  • Preferred experience with reasoning models, agents, planning systems, or multi-step ML orchestration.
  • Preferred experience designing antibodies, nanobodies, enzymes, peptides, or other therapeutic proteins in design-test-learn loops.
  • Preferred experience developing evaluation harnesses, model registries, or benchmark suites.
  • Preferred experience training or serving models at scale, including distributed training, GPU efficiency, or high-throughput inference.
  • Publications, open-source contributions, or applied research outputs in AI for Science are a plus.

Benefits

  • Competitive base compensation with bonus potential and generous early-stage equity.
  • U.S. full-time employees receive medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off; company-wide holidays; paid parental leave; educational assistance; commuter benefits including bike share memberships for office-based employees; and a subsidized lunch program.
  • International full-time employees receive a comprehensive benefits program tailored to their region.
  • Full-time employment; U.S. base salary range is $176,000–$304,000.

Categories

Lila Sciences

About Lila Sciences

501-1,000 employees

Lila Sciences builds an AI-driven research platform and autonomous lab systems for life science, chemistry, and materials R&D teams. Its products combine large AI models with robotic instruments to plan, run, and analyze experiments, integrating into customer-specific scientific workflows. The privately held company serves pharma, materials, and energy organizations and is venture-backed, including a Series A financing in 2025.

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