eClinical Solutions

Principal Software Architect

eClinical Solutions
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5 days ago
Remote, United StatesStaff+

Base Salary

$168k - $210k/yr

Responsibilities

  • Lead the design and evolution of scalable, secure, and responsible AI-enabled software platforms.
  • Evaluate emerging AI, machine learning, generative AI, cloud, and software architecture technologies for product fit.
  • Analyze features, data flows, and system designs for scalability, performance, security, and AI readiness.
  • Define and document reference architectures covering data ingestion, retrieval-augmented generation, model integration, inference services, monitoring, and human-in-the-loop workflows.
  • Guide responsible AI practices involving privacy, security, explainability, bias mitigation, regulatory awareness, governance, and enterprise data protection.
  • Help teams integrate LLMs and AI services into .NET- and Python-based systems and build AI-assisted workflows, copilots, and intelligent automation.
  • Apply prompt engineering, evaluation techniques, guardrails, and agentic AI patterns to production systems.
  • Mentor architects and engineers and influence technical strategy across product, engineering, security, data, and business stakeholders.

Requirements

  • 10+ years in web application development, service-oriented architecture, cloud-native platforms, and AI-enabled application design preferred.
  • 10+ years in full-stack enterprise application development with experience integrating AI, automation, analytics, or data-driven capabilities preferred.
  • 10+ years leading software engineering teams and mentoring architects and engineers on AI adoption, architectural trade-offs, and modern delivery practices preferred.
  • Mastery of software architecture and design, including AI-enabled system design patterns.
  • Deep understanding of Microsoft .NET and modern application integration patterns for AI-enabled services.
  • Expertise in relational and non-relational database design, data modeling, and data architecture for analytics and AI use cases.
  • Experience with enterprise SaaS cloud environments and scalable deployment patterns for AI, ML, and data-intensive workloads.
  • Knowledge of AWS products and deployment, including cloud AI services, model hosting, automation, monitoring, and secure integration patterns.
  • Familiarity with model lifecycle management, prompt engineering, retrieval-augmented generation, evaluation frameworks, observability, and MLOps practices.
  • Ability to evaluate technologies and communicate comparative benefits, risks, costs, and implementation considerations.
  • Strong problem-solving, written communication, verbal communication, and cross-functional influence skills.
  • Understanding of responsible AI, privacy, security, compliance, governance, and enterprise data protection.

Benefits

  • Remote work is supported; eClinical Solutions received the 2025 Top Workplaces USA Award for Remote Work.
  • The company promotes an inclusive, people-first culture with opportunities to learn, grow, and continuously improve.
  • Equal opportunity employment and a workplace that values diversity are emphasized.

Tech Stack

eClinical Solutions

About eClinical Solutions

501-1,000 employees
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