AstraZeneca

Principal Scientist, Generative AI

AstraZeneca
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2 hours ago
Beijing, ChinaStaff+

Responsibilities

  • Collaborate with scientists across drug development to understand challenges and build platforms supporting their research.
  • Build generative AI prototypes that accelerate routine scientific processes and demonstrate business value.
  • Design and deploy machine learning models for large-scale clinical transcriptomics, proteomics, and cell painting analysis.
  • Design agentic AI workflows integrating bioinformatics and machine learning analysis steps.
  • Calculate project ROI and impact using information and assumptions gathered from stakeholders and future users.
  • Provide strategic direction for generative AI adoption and help define and implement the organization’s generative AI strategy.
  • Ensure infrastructure and platforms support scaling exploratory research into production solutions.
  • Manage stakeholder relationships, communicate results and uncertainties clearly, and drive utilization of information resources and services.
  • Improve machine learning development environments, platforms, and tooling.
  • Coordinate with global AI research teams across China, India, Europe, and the US East Coast.
  • Collaborate with cybersecurity, data privacy, governance, and compliance functions to secure computing environments while supporting productivity.

Requirements

  • Bachelor’s or master’s degree, or equivalent years of experience, in mathematics, computer science, engineering, physics, statistics, computational sciences, or a related field.
  • Advanced Python programming and experience with AI libraries and frameworks such as TensorFlow and PyTorch.
  • Proven experience in AI and machine learning, including areas such as deep learning, natural language processing, computer vision, and reinforcement learning.
  • Experience with prompt engineering, Retrieval-Augmented Generation, and LLM fine-tuning.
  • Experience implementing generative AI workflows using large language models, foundation models, or agentic frameworks, ideally in pharma or healthcare.
  • Experience analyzing large, high-dimensional, unstructured datasets and communicating conclusions and recommended actions to stakeholders.
  • Experience designing agentic AI workflows and planning strategically for AI needs in a large organization.
  • Strong knowledge of software development and machine learning deployment principles.
  • Familiarity with CNNs, vision transformers, diffusion models, ResNet, UNet, DINO, CLIP, and Stable Diffusion.
  • Familiarity with GitHub, CI/CD pipelines, DevOps, and MLOps practices.
  • Demonstrable experience with AWS or a similar cloud environment.
  • Experience with Kubernetes and container-based application deployments.
  • Excellent communication and presentation skills for explaining complex AI concepts to non-technical partners.
  • Strong leadership and project management skills with a record of leading successful AI projects.
  • Knowledge of AI ethics and responsible AI practices.
  • Experience in life sciences, healthcare, or pharmaceuticals is desirable.
  • Experience working in a complex global organization is desirable.
  • Experience with LLM frameworks such as LangChain, AutoGen, and LlamaIndex is desirable.
  • Experience with foundation models for transcriptomics or Cell Painting data, such as Geneformer, scGPT, and scFoundation, is desirable.
  • Publications in top AI conferences or journals such as NeurIPS, ICML, Nature Machine Intelligence, Nature Communications, or NEJM AI are desirable.

Tech Stack

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AstraZeneca

About AstraZeneca

10,000+ employees

We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. For more information, visit www.astrazeneca.com. Community Guidelines: bit.ly/2MgAcio

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