AstraZeneca

Principal AI Engineer - Evinova

AstraZeneca
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5 days ago
Gaithersburg, MD, USAStaff+
H1B sponsor

Base Salary

$145k - $190k/yr

Responsibilities

  • Design and deploy sophisticated agentic AI systems using state-of-the-art large language models.
  • Develop agent memory, tool-use, multi-agent collaboration, retrieval, information extraction, structured generation, and graph-reasoning capabilities.
  • Create automated approaches for agent design, evaluation, prompt optimization, and performance monitoring.
  • Build observability pipelines for continuous model and agent monitoring.
  • Partner with product, design, clinical, and ML teams to translate AI capabilities into healthcare solutions.
  • Mentor engineers and contribute to organizational AI strategy.
  • Share expertise through conferences, technical publications, and open-source projects.

Requirements

  • Bachelor's degree in engineering, mathematics, or computer science.
  • At least 4 years of applied machine learning experience focused on deep learning, NLP, and generative AI.
  • Extensive experience exploring language model behavior, prompting, and building products with language models.
  • Expert knowledge of Python and advanced ML/LLM frameworks such as TensorFlow, PyTorch, Google ADK, CrewAI, LangChain, and LlamaIndex.
  • Extensive experience with AWS services including SageMaker, Bedrock, MSK, EKS, ECS, and OpenSearch.
  • Strong understanding of agentic AI systems, agentic design patterns, multi-agent systems, and reinforcement learning.
  • Excellent communication skills for explaining complex technical concepts to technical and non-technical audiences.
  • Preferred qualifications include a relevant Ph.D., technical leadership on large-scale AI projects, complex LLM-based agentic systems experience, C/C++, Rust, or CUDA experience, open-source AI contributions, expertise in few-shot learning, meta-learning, explainable AI, and responsible AI or life sciences regulatory experience.

Benefits

  • Hybrid work with employees expected to work from the office three days per week.
  • Annual base pay ranges from $144,648.80 to $189,851.55 USD.
  • Short-term incentive bonus opportunity and eligibility for an equity-based long-term incentive program.
  • Benefits include a qualified retirement program with a 401(k) plan, paid vacation and holidays, paid leaves, and medical, prescription drug, dental, and vision coverage.
  • The position is an at-will employment role.
  • Applications are requested by the November 12, 2026 closing date.

Tech Stack

Categories

AstraZeneca

About AstraZeneca

10,000+ employees

AstraZeneca is a global biopharmaceutical company that discovers, develops, manufactures, and commercializes prescription medicines for patients and healthcare systems. Its portfolio spans oncology, cardiovascular, renal and metabolism, respiratory and immunology, and rare diseases (expanded by the 2021 acquisition of Alexion). Founded in 1999 and headquartered in Cambridge, UK, it is a public company listed on the London Stock Exchange and Nasdaq, generating revenue primarily from drug sales and partnerships.

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