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Astera Institute

Senior/Staff AI Scientist (Polytope Bio)

Astera Institute
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about 4 hours ago
San Francisco, CA, USA or New York, NY, USASenior / Staff+
H1B Sponsor

Base Salary

$200k - $300k/yr

Responsibilities

  • Drive core research by developing and executing the scientific vision.
  • Design and implement reinforcement learning feedback loops for biological language models.
  • Work hands-on with the technical team to build and debug model training infrastructure.
  • Collaborate with the experimental team to ensure cohesive system design between lab measurements and model learning.

Requirements

  • PhD in machine learning, computational biology, or a related field with 1-2 years of post-PhD experience.
  • Experience training models from scratch and debugging training runs.
  • Hands-on experience with generative diffusion models and transformer architectures.
  • Familiarity with modern reinforcement learning and preference-optimization methods.
  • A strong research track record demonstrated through publications or open-source work.
  • An entrepreneurial spirit and comfort with ambiguity.

Benefits

  • Base salary of $200,000 to $300,000 during the residency.
  • Potential to evolve into a co-founding technical role in a future spinout.
  • Authorship of high-impact open-source datasets, methods, and models.
  • Access to significant secured runway and dedicated GPU resources.
  • A unique environment combining frontier ML work with high-throughput experimental capabilities.
  • Comprehensive benefits package including health insurance and retirement plan.

Categories

AI & MLData Science