Senior ML Engineer
Flagship Pioneering, Inc.14 hours ago
Responsibilities
- Design, build, and deploy ML systems for retrieval, summarization, classification, and agentic reasoning.
- Architect scalable RAG and LLM-based systems integrating structured data, documents, and knowledge graphs.
- Build and maintain agentic orchestration frameworks for LLM-based agents.
- Own data collection, cleaning, feature engineering, labeling, training, evaluation, deployment, monitoring, and post-deployment iteration.
- Fine-tune and evaluate LLMs and other models for production reliability, latency, and cost.
- Establish lightweight MLOps practices covering model CI/CD, reproducibility, and experiment tracking.
- Balance third-party APIs such as OpenAI and Anthropic with custom-built or fine-tuned solutions.
- Influence architecture decisions and define ML best practices across the team.
- Collaborate with data engineering, product, scientists, researchers, and domain experts.
- Communicate technical findings and tradeoffs to technical and non-technical stakeholders.
Requirements
- Master's degree or above in Computer Science, Machine Learning, AI, or a related field, or equivalent practical experience.
- At least 5 years of professional applied machine learning experience.
- Strong foundations in machine learning, deep learning, and natural language processing.
- Production experience deploying LLM-powered applications using frameworks such as PyTorch, vLLM, or LangGraph.
- Hands-on experience with RAG, agentic orchestration, or multi-agent systems is strongly preferred.
- Proficiency in Python and tools for ML development, large-scale data pipelines, and standard evaluation protocols.
- Experience owning production systems end to end, including monitoring and post-deployment iteration.
- Strong communication and presentation skills for working with technical and non-technical collaborators.
- Startup experience is a plus.
- Publications at NeurIPS, ICML, ACL, or EMNLP are a bonus.
Benefits
- Healthcare coverage, an annual incentive program, retirement benefits, and a broad range of other benefits are offered.
- The posting states that compensation and benefits information is based on the employer's good-faith estimate and may be modified in the future.
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About Flagship Pioneering, Inc.
Flagship Pioneering invents, builds, and finances platform biotechnology companies in human health and sustainability, providing founding science, capital, and operational support to entrepreneurs and researchers. The privately held firm, founded in 2000 and headquartered in Cambridge, MA, has originated more than 100 ventures and maintains an ecosystem of 40+ companies. Notable portfolio companies include Moderna, Denali Therapeutics, Generate:Biomedicines, Indigo Agriculture, and Tessera Therapeutics.