Flagship Pioneering, Inc.

Flagship Pioneering, Inc.

Visit websiteLinkedIn501-1,000 employeesH1B sponsor

Flagship Pioneering invents, builds, and finances platform biotechnology companies in human health and sustainability, providing founding science, capital, and operational support to entrepreneurs and researchers. The privately held firm, founded in 2000 and headquartered in Cambridge, MA, has originated more than 100 ventures and maintains an ecosystem of 40+ companies. Notable portfolio companies include Moderna, Denali Therapeutics, Generate:Biomedicines, Indigo Agriculture, and Tessera Therapeutics.

Open Positions at Flagship Pioneering, Inc.

9 open positions

Cambridge, MA, USASenior / Staff+
$108k - $209k/yr

Lead the development of customer-facing, AI-enabled applications across the front-end and back-end stack at an early-stage company focused on psychological fitness and wellbeing. This role combines hands-on software development, product ownership, architecture, and cross-functional technical leadership.

Cambridge, MA, USAMid Level
$120k - $193k/yr

FL105 is seeking a Machine Learning Research Engineer to develop and deploy advanced ML and LLM-powered applications for psychological wellbeing. The role combines machine learning research, human-feedback learning, agentic AI, and production deployment in an interdisciplinary startup environment.

3 days ago
Cambridge, MA, USAStaff+
$108k - $176k/yr

Build and lead the hands-on implementation of AI-powered tools and workflows for Flagship Pioneering’s legal department. This role sits at the intersection of AI engineering, legal operations, governance, and cross-functional enablement.

1 month ago
Cambridge, MA, USAStaff+
$188k - $259k/yr

Lead the architecture and delivery of scalable backend systems powering an agentic AI platform. This principal-level role combines distributed services, data pipelines, third-party integrations, and hands-on work improving AI agent experiences.

Cambridge, United KingdomSenior

Lead the architecture and operation of AWS-based data, cloud, and AI infrastructure supporting Quotient’s genomics-first drug discovery platform. This senior individual-contributor role combines hands-on platform engineering, technical leadership, incident ownership, and mentoring in a research-intensive biotech environment.

1 month ago
Cambridge, MA, USAStaff+
$216k - $297k/yr

Join Pioneering Intelligence as a Principal ML Scientist to lead the development of multimodal biological reasoning engines that integrate AI and biological data for groundbreaking scientific discovery.

3 months ago
Cambridge, MA, USAStaff+
$188k - $258k/yr

Own the platform foundation that makes long-running, multi-agent scientific AI workflows reliable in production. This hands-on principal role combines distributed-systems architecture, cloud infrastructure, agentic AI orchestration, and technical leadership.

4 months ago
Cambridge, MA, USAStaff+
$148k - $204k/yr

Build and lead Flagship Pioneering’s cloud security and AppSec engineering practice across its AWS environments and portfolio companies. You’ll embed security into engineering pipelines while creating AI-augmented workflows that automate routine security work and preserve expert focus for complex judgment.

5 months ago
Cambridge, MA, USAAny Level

Join Flagship Labs 109, Inc. as part of an innovative team focused on leveraging AI, physics, and hardware to revolutionize molecular biology.

5 months ago
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