
Flagship Pioneering, Inc.
Flagship Pioneering invents, builds, and finances platform biotechnology companies in human health and sustainability, providing founding science, capital, and operational support to entrepreneurs and researchers. The privately held firm, founded in 2000 and headquartered in Cambridge, MA, has originated more than 100 ventures and maintains an ecosystem of 40+ companies. Notable portfolio companies include Moderna, Denali Therapeutics, Generate:Biomedicines, Indigo Agriculture, and Tessera Therapeutics.
Open Positions at Flagship Pioneering, Inc.
14 open positions
Build and operate a biological research data platform that connects computational workflows, experimental records, and analysis-ready data. This hands-on role focuses on data modeling, pipeline automation, APIs, cloud infrastructure, and reliable collaboration with experimental scientists.
Senior ML Engineer building and deploying production machine learning systems focused on LLMs, RAG, agentic orchestration, and multimodal data. The role spans the full ML lifecycle and includes shaping architecture and best practices across the team.
Explore ambitious AI and machine learning applications for scientific and entrepreneurial challenges at Flagship Pioneering. You will design, implement, benchmark, and evaluate innovative ML workflows using scalable GPU resources and ecosystem data.
Principal Data Engineer at Vesalius Therapeutics, supporting the programmable infrastructure behind a human cellular biology platform focused on developing new medicines. The posting provides limited role-specific detail but highlights the company’s work across genetics, genomics, cellular biology, and artificial intelligence.
Lead the engineering and automation that powers Microsoft 365 and Entra ID identity lifecycle management across Flagship Pioneering and its portfolio companies. This hands-on individual contributor role combines production coding, platform operations, and senior escalation support.
Senior Software Engineer owning backend, data pipeline, and EHR integration systems that transform healthcare data into trusted clinical results. The role spans AWS infrastructure, AI/ML production operations, partner technical go-lives, and early-stage engineering foundation building.
Build and own the scalable data infrastructure that makes proteomics data discoverable, trustworthy, and ready for machine learning. This hands-on technical leadership role partners closely with scientists to turn experimental data into production-grade systems.
Lead Bioinformatics Engineer owning a portfolio-wide bioinformatics platform, reusable workflow frameworks, and genomic data access partnerships. The role combines production bioinformatics engineering with enablement of scientific teams across Flagship’s portfolio.
Lead the development of customer-facing, AI-enabled applications across the front-end and back-end stack at an early-stage company focused on psychological fitness and wellbeing. This role combines hands-on software development, product ownership, architecture, and cross-functional technical leadership.
Lead Data Engineer responsible for modernizing cloud-native data infrastructure, platforms, and pipelines supporting scientific and biotech organizations. This senior individual-contributor role combines hands-on data engineering, technical leadership, platform reliability, and cross-functional collaboration.
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