Amgen

Senior Machine Learning Engineer

Amgen
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1 day ago
Remote, United States or Thousand Oaks, CA, USASenior

Base Salary

$156k - $211k/yr

Responsibilities

  • Build scalable AI proofs of concept designed to progress from prototypes to enterprise-scale solutions.
  • Partner with product managers, business stakeholders, platform teams, and AI software engineers to translate ambiguous needs into measurable AI solutions.
  • Design and implement AI systems using LLMs, agentic workflows, retrieval-augmented generation, data pipelines, APIs, cloud-native services, and enterprise platforms.
  • Evaluate technical risk, data readiness, integration complexity, user experience, security, performance, cost, and business impact.
  • Create reusable reference architectures, components, documentation, decision records, and handoff materials.
  • Mentor others, improve engineering practices and delivery patterns, and provide ownership in uncertain, fast-moving work.

Requirements

  • Doctorate degree, or a master’s degree with 2 years of relevant experience, bachelor’s degree with 4 years, associate’s degree with 8 years, or high school diploma/GED with 10 years of relevant experience.
  • Preferred 4–6 years of relevant experience in AI engineering, machine learning engineering, software engineering, data engineering, cloud engineering, or related technical roles.
  • Experience building scalable, secure, evaluated, maintainable full-stack AI applications beyond experimentation.
  • Strong understanding of LLMs, retrieval-augmented generation, embeddings, vector databases, agentic workflows, tool use, orchestration frameworks, and AI evaluation methods.
  • Experience evaluating AI solutions for accuracy, reliability, hallucination risk, latency, usability, safety, cost, and fitness for intended use.
  • Experience with AWS Cloud, data pipelines, integration architecture, containers, CI/CD, observability, and secure development practices.
  • Strong software engineering foundation, preferably with Python, testing, version control, modular design, documentation, and maintainable code.
  • Ability to use AI tools responsibly to improve engineering productivity and automate repetitive tasks.
  • Strong communication, ownership, and cross-functional leadership skills.

Benefits

  • Comprehensive benefits package including retirement and savings contributions, medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • Discretionary annual bonus program and stock-based long-term incentives.
  • Award-winning time-off plans.
  • Flexible work models where possible.
  • Career development opportunities and work/life balance support.

Tech Stack

Categories

Amgen

About Amgen

10,000+ employees

Amgen is a public biotechnology company that discovers, develops, manufactures, and sells biologic and biosimilar therapeutics for patients with serious diseases. Its portfolio and pipeline span oncology, cardiovascular disease, osteoporosis, inflammation, and rare diseases, marketed globally through direct sales and partnerships. Founded in 1980 and headquartered in Thousand Oaks, California (NASDAQ: AMGN), Amgen is a component of the Dow Jones Industrial Average and completed the acquisition of Horizon Therapeutics in 2023.

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