AstraZeneca

Principal Product Engineer - Evinova

AstraZeneca
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2 hours ago
Gaithersburg, MD, USAStaff+
H1B sponsor

Base Salary

$172k - $259k/yr

Responsibilities

  • Design and build AI-powered product features including agent architectures, RAG pipelines, model orchestration, evaluation frameworks, and guardrails.
  • Own end-to-end technical decisions across application code, data stores, infrastructure, deployment, observability, cost, and security.
  • Set technical direction for embedded product teams and make architecture decisions that balance prototyping speed with long-term durability.
  • Mentor and coach engineers through pairing, design review, judgment transfer, and technical leadership.
  • Assess system constraints, dependencies, failure modes, reversibility, and the blast radius of technical decisions.
  • Build production AI systems that are testable, versioned, evaluated, observable, and capable of graceful degradation.

Requirements

  • Bachelor's degree.
  • Minimum 8+ years of experience in software engineering, including meaningful time at a senior, staff, or principal level owning technical direction.
  • Production experience building and shipping AI-powered features such as agent systems, RAG, or model orchestration.
  • Strong full-stack capability across application code, data stores, and infrastructure.
  • Experience designing, deploying, and operating production systems on AWS at scale.
  • Demonstrated ability to mentor and elevate other engineers through pairing, design reviews, or informal technical leadership.
  • Preferred experience in regulated industries such as healthcare, pharma, or finance.
  • Preferred background building multi-agent or agentic AI systems in production.
  • Preferred familiarity with infrastructure as code such as CDK, Terraform, or Pulumi and container orchestration such as EKS or ECS.
  • Preferred experience in product-led engineering organizations where engineers own outcomes.

Benefits

  • Annual base pay ranges from $172,466.00 to $258,700.00 USD.
  • Short-term incentive bonus opportunity and eligibility for an equity-based long-term incentive program for salaried roles.
  • Qualified retirement program including a 401(k) plan, paid vacation and holidays, paid leaves, and medical, prescription drug, dental, and vision coverage.
  • In-person work averages a minimum of three days per week in the office, with individual flexibility around the expectation.
  • The position is at-will and was posted on 24-Aug-2026 with a closing date of 07-Sep-2026.

Tech Stack

Amazon DynamoDBApache KafkaAWSFastAPIGitHub ActionsKubernetesMongoDBNext.jsNode.jsPostgreSQLPrometheusPythonReactTailwind CSSTerraformTypeScript
AstraZeneca

About AstraZeneca

10,000+ employees

We're transforming the future of healthcare by unlocking the power of what science can do for people, society and the planet. For more information, visit www.astrazeneca.com. Community Guidelines: bit.ly/2MgAcio

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