6 months ago
Oakland, CA, USAMid Level / Senior / Staff+
Base Salary
$160k - $230k/yr
Responsibilities
- Lead design and implementation of scalable NGS analysis pipelines supporting gene editing and protein engineering workflows.
- Develop clear, intuitive visualizations and reports to communicate sequencing results and biological insights.
- Manage cloud-based compute environments and data systems for large-scale datasets.
- Partner with biology teams to analyze results, troubleshoot, and optimize experimental design.
- Collaborate with machine learning teams to curate data for model training.
- Establish best practices for code review, testing, and CI/CD in computational workflows.
- Mentor junior scientists and foster a culture of rigor, reproducibility, and innovation.
Requirements
- PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field.
- 5+ years of experience analyzing NGS datasets.
- Strong programming skills in Python (pandas, numpy, biopython, etc.).
- Expertise with workflow orchestration tools (Nextflow, Snakemake) and cloud environments (GCP, AWS).
- Experience with containerization (Docker, Kubernetes) and scalable compute infrastructure.
- Deep understanding of Linux, git-based version control, and software engineering best practices.
- Proven ability to transform complex sequencing data into actionable biological insights.
Benefits
- High-growth opportunity with meaningful impact on the future of protein design.
- Competitive compensation package with equity participation.
- 401(k) with a strong employer match.
- Comprehensive benefits including health/dental/vision insurance.
- Generous PTO policy and commitment to work-life balance.
- Professional development opportunities in a cutting-edge field at the intersection of AI and biology.
Tech Stack
Categories
BackendData Science
About Profluent
Profluent builds generative AI models to design and experimentally validate novel proteins, with applications in therapeutics, gene editing, and other areas of biomedicine. The company combines large-scale foundation models with wet-lab screening to create functional molecules for partners and internal programs. Founded in 2022 and headquartered in Emeryville, California, Profluent is privately held.