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Profluent

Lead Bioinformatics Scientist, NGS

Profluent
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about 1 month ago
Oakland, CA, USAMid Level / Senior / Staff+

Base Salary

$160k - $230k/yr

Responsibilities

  • Lead design and implementation of scalable NGS analysis pipelines supporting gene editing and protein engineering workflows.
  • Develop clear, intuitive visualizations and reports to communicate sequencing results and biological insights.
  • Manage cloud-based compute environments and data systems for large-scale datasets.
  • Partner with biology teams to analyze results, troubleshoot, and optimize experimental design.
  • Collaborate with machine learning teams to curate data for model training.
  • Establish best practices for code review, testing, and CI/CD in computational workflows.
  • Mentor junior scientists and foster a culture of rigor, reproducibility, and innovation.

Requirements

  • PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field.
  • 5+ years of experience analyzing NGS datasets.
  • Strong programming skills in Python (pandas, numpy, biopython, etc.).
  • Expertise with workflow orchestration tools (Nextflow, Snakemake) and cloud environments (GCP, AWS).
  • Experience with containerization (Docker, Kubernetes) and scalable compute infrastructure.
  • Deep understanding of Linux, git-based version control, and software engineering best practices.
  • Proven ability to transform complex sequencing data into actionable biological insights.

Benefits

  • High-growth opportunity with meaningful impact on the future of protein design.
  • Competitive compensation package with equity participation.
  • 401(k) with a strong employer match.
  • Comprehensive benefits including health/dental/vision insurance.
  • Generous PTO policy and commitment to work-life balance.
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology.

Tech Stack

AWSDockerGitGoogle Cloud PlatformKubernetesLinuxNumPyPandasPythonSQL

Categories

AI & MLBackendData Science