Natera

Senior Software Engineer, AI Governance

Natera
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3 hours ago
Remote, United StatesSenior
H1B sponsor

Base Salary

$125k - $156k/yr

Responsibilities

  • Build and own guardrails in the LLM Gateway, including content filtering, output validation, PHI/PII detection, prompt-injection defenses, session retention, and audit logging.
  • Engineer policy enforcement, risk-based output routing, retrieval filtering, citation checks, and PHI exposure prevention for agentic and RAG systems.
  • Implement observability, accuracy and drift monitoring, misuse alerting, escalation thresholds, and AI incident-response tooling.
  • Build automated AI risk intake, scoring, tiering, routing, and an auditable AI Risk Register aligned with applicable governance frameworks.
  • Run AI use-case intake and high-risk governance reviews with Legal, Privacy, RAQA, and business stakeholders.
  • Own technical due diligence for AI vendors and foundation-model providers, including data residency, API security, transparency, contractual controls, and regulatory alignment.
  • Help maintain AI acceptable-use policies and advise engineering teams on implementing governance controls.

Requirements

  • 7+ years of software engineering experience, including at least 3 years working directly with AI/ML systems, LLM infrastructure, or AI safety and governance engineering.
  • Hands-on experience building production AI systems such as LLM pipelines, RAG architectures, agentic runtimes, or AI observability and monitoring infrastructure.
  • Practical experience mitigating hallucination, bias, prompt injection, data leakage, and model drift in production.
  • Proficiency in Python and experience building production API integrations, middleware, and data pipelines.
  • Experience with ML observability and monitoring, including instrumentation, drift thresholds, and alerting.
  • Experience in healthcare, life sciences, financial services, or another regulated environment with HIPAA-equivalent obligations and PHI/PII handling.
  • Working knowledge of NIST AI RMF or ISO 42001 applied through technical controls.
  • Ability to write technical specifications and documentation for engineering and Legal audiences.
  • Preferred experience with LLM gateways, RAG controls, content moderation, agentic AI safety, AI red-teaming, adversarial testing, structured model evaluation, or trust and safety infrastructure.
  • Preferred experience with Arize, Fiddler, Whylogs, diagnostics, genomics, clinical AI, HIPAA, FDA GxP, GMLP, GMP, GCP, CLIA, PMDA, GDPR, CIPP, CIPT, or Responsible AI credentials.

Benefits

  • Remote USA work arrangement.
  • Medical, dental, vision, life, and disability plans for eligible employees and dependents.
  • Free testing for Natera employees and immediate family members, plus fertility care benefits.
  • Pregnancy and baby bonding leave, 401k benefits, commuter benefits, and an employee referral program.
Natera

About Natera

5,001-10,000 employees

Natera develops and sells cell-free DNA-based diagnostic tests for oncology, women’s health, and organ transplant care, used by hospitals and clinicians. Its portfolio includes non-invasive prenatal testing and carrier screening, minimal residual disease monitoring for cancer, and transplant rejection assessment, delivered as CLIA/CAP-accredited lab services. Founded in 2004 and headquartered in Austin, Texas, Natera is a public company listed on NASDAQ.

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